Saturday 30 August 2014

[Z615.Ebook] PDF Ebook Learning To Speak, by Kat Savage

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Learning To Speak, by Kat Savage

n Learning To Speak, Kat Savage draws the parallel between the loves we experience and how we often lose our voices in the process. From the beginnings both heartbreaking and hopeful, to the loss, to the "aha" moment when we realize we are going to be okay, her first collection of poetry is meant to be a journey. She hopes we will all ask ourselves: How many times have you lost your voice to someone who isn't even listening?

  • Sales Rank: #1927401 in Books
  • Published on: 2015-10-30
  • Original language: English
  • Number of items: 1
  • Dimensions: 9.02" h x .44" w x 5.98" l, .79 pounds
  • Binding: Hardcover
  • 128 pages

Most helpful customer reviews

1 of 1 people found the following review helpful.
So many of these feel like something my heart has tried to speak but could ...
By Carlyn
So many of these feel like something my heart has tried to speak but could not put into words. Kat Savage does so beautifully. I'm purchasing her latest release ,"Mad Woman" now. I can't get enough.

1 of 1 people found the following review helpful.
If you are looking to put your broken heart to rest and some awesome inspiration to be an independent women this is an ...
By becky
Straight from the heart. If you are looking to put your broken heart to rest and some awesome inspiration to be an independent women this is an amazing read. I feel that my soul has a sister now

1 of 1 people found the following review helpful.
Five Stars
By B-DawkX20
Fantastic book. Beautifully heartbreaking in all the best ways. Highly recommended.

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Monday 25 August 2014

[F903.Ebook] Ebook Download Michelin Green Guide Bordeaux, Aquitaine & the Basque Country: French Atlantic Coast (Green Guide/Michelin), by Michelin Travel & Lifestyl

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Michelin Green Guide Bordeaux, Aquitaine & the Basque Country: French Atlantic Coast (Green Guide/Michelin), by Michelin Travel & Lifestyl

Discover Bordeaux, famous for its wines and nearby M�doc and St-�milion vineyards. Then head for the lively Basque coast towns of Biarritz or St-Jean-de-Luz. Divided into regions for easy travel planning, the guide offers suggestions for what to see and do in Aquitaine, details walking/driving tours and excursions, and delves into art, culture and history. With plenty of color photos and maps, and recommendations for the best places to eat and stay, the Michelin Green Guide Bordeaux, Aquitaine & the Basque Country is the only guide you’ll need.

  • Sales Rank: #145041 in Books
  • Published on: 2014-02-07
  • Original language: French
  • Number of items: 1
  • Dimensions: 8.50" h x .49" w x 4.67" l, .68 pounds
  • Binding: Paperback
  • 320 pages

Most helpful customer reviews

2 of 2 people found the following review helpful.
A guide with a different perspective
By debby lai
This is an extraordinary travel guide. There are many sights and suggestions (of eateries and lodgings, in particular) that are not included in other guide books. The tips on traveling by car are good, especially considering that it carries the "Michelin" flag. All in all, the layout and contents give readers a fresh perspective when planning to travel to the Bordeaux and Aquitaine region.

2 of 2 people found the following review helpful.
Coverage is not consistant with Michelin Map of Aquitaine
By Eugene T Mollica Jr
The Green Guide, which indicates coverage of Aquitaine, does not cover the same area as the Michelin Map No.524 titled Aquitaine, leaving important cities such as Perigueux out of the Green Guide. I think the two publications should cover the same areas.

1 of 1 people found the following review helpful.
A Disappointment
By Harriet Fraad
disappointment. The previous green guides were vastly superiorA

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Michelin Green Guide Bordeaux, Aquitaine & the Basque Country: French Atlantic Coast (Green Guide/Michelin), by Michelin Travel & Lifestyl PDF
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Sunday 24 August 2014

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  • Sales Rank: #56059 in eBooks
  • Published on: 2015-11-03
  • Released on: 2015-11-03
  • Format: Kindle eBook

Most helpful customer reviews

3 of 3 people found the following review helpful.
A good buy!
By regine soriano
This is a good book to read for all those mothers who wants to make sweet candies for their children. all the preparation can be made in your kitchen with ease. very easy to understand this book has been a great addition to my confections book shelf. I have found the recipes to be very reliable.Book is good. Learned new things from this book about different types of fudges and candies. I will suggest this book to all who loves cooking . all the preparation can be made in your kitchen with ease. very easy to understand and it helps a lot. all in all a good book to read. The recipes are simply superb :)

3 of 3 people found the following review helpful.
OMG, I am in love with this. Thanks or amazing recipes
By Angela May Bloomberg
Oh wow, 60 fudge recipes, this is something. I love fudges very very much. I have read this book thoroughly; I found many useful tips on fudge making. I also found many interesting and new recipes for me. Great! Thanks so much. I especially liked Caramel Peanut Fudge, Cherries and Chocolate Fudge, Chocolate Sour Cream Fudge and Fudge Bonbons. Many thanks!

1 of 1 people found the following review helpful.
Decadent Holiday Deliciousness
By UtahGeekGrl
can you say decadent? OMG... strawberry fudge... need I say more? D.A. Wheeler has done it again with an amazing collection of yummy treats just in time for the holidays.... I can't wait to put together gift boxes of assorted fudge for my friends for Christmas!

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Friday 22 August 2014

[B394.Ebook] PDF Download Creating True Prosperity, by Shakti Gawain

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Creating True Prosperity, by Shakti Gawain

Personal-growth expert Shakti Gawain redefines prosperity in a moving testament to the power of fulfilling the soul. Gawain, author of Creative Visualization, presents a new definition of prosperity, one that recognizes the true importance of fulfillment of the heart and soul rather than of monetary gain.

  • Sales Rank: #112344 in Books
  • Published on: 1997-01
  • Original language: English
  • Number of items: 1
  • Dimensions: .89" h x 5.28" w x 7.57" l,
  • Binding: Hardcover
  • 179 pages

From AudioFile
Best-known for her classic, Creative Visualization, Gawain offers here a larger outlook on prosperity, one beyond the normal limits of money. She first examines three perspectives on prosperity: materialistic philosophy, New Age thought, and a transcendent spiritual viewpoint. On the level of the individual, true prosperity means balance, personal satisfaction and fulfilling relationships. Integral to this experience of prosperity is the balancing of polarities: active and receptive, giving and receiving, doing and being. The author, a casual yet careful reader, delivers her material with gentleness, humor and com-passion. The technical quality of the recording is excellent. Creating True Prosperity is certain to be popular among Gawain fans and among listeners interested in a more metaphysical perspective on money. C.S. (c)AudioFile, Portland, Maine

Most helpful customer reviews

2 of 2 people found the following review helpful.
Flawless In Content...Killer in Formatting
By Ricky Don't Lose That Number
This is a fantastic book, filled with great advice. I almost didn't give it 5-stars because of the poor formatting, but why create the karma. : ) If anyone at Shakti's publishing firm is reading this, much of the text appears squished together on a Kindle Fire. Much of the wording has no space between them, which makes it difficult to get through. It's probably that it was formatted way back when, before eReaders were really popular. It's to the point where at times you can't even read sections. But I obviously chugged through it because of the powerful messages. That says something about this book!

0 of 0 people found the following review helpful.
Five Stars
By Kelly Weeks
As promised.

1 of 1 people found the following review helpful.
awareness
By sylviascarlet
This book is very good at helping you become aware of beliefs that you might subconsciously entertain that prevent you from either experiencing or seeing prosperity in your life.

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Wednesday 20 August 2014

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Beginning XNA 2.0 Game Programming: From Novice to Professional, by Alexandre Santos Lobao, Bruno Evangelista, Jose ANTONIO LEAL DEFARIAS

Beginning XNA 2.0 Game Programming: From Novice to Professional, by Alexandre Santos Lobao, Bruno Evangelista, Jose ANTONIO LEAL DEFARIAS



Beginning XNA 2.0 Game Programming: From Novice to Professional, by Alexandre Santos Lobao, Bruno Evangelista, Jose ANTONIO LEAL DEFARIAS

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Beginning XNA 2.0 Game Programming: From Novice to Professional, by Alexandre Santos Lobao, Bruno Evangelista, Jose ANTONIO LEAL DEFARIAS

XNA makes it simple to create your own games, which will run on a PC and Xbox 360 console. Even if you don’t know how to program at all, Beginning XNA Game Programming will teach you the basics of C# 2005 programming along the way. This fast-paced introduction to XNA and the C# language provides professional developers a quick-start guide to creating a commercial product using XNA, as well as offering home enthusiasts or hobbyists everything they need to begin putting together games in their spare time. You’ll discover and understand all the key concepts required to create smooth, professional-looking results in a range of gaming genres.

  • Published on: 2010-11-16
  • Number of items: 1
  • Binding: Paperback
  • 456 pages

About the Author
Alexandre Lob o is a passionate man. His first passion was reading, starting with large books Mark Twain, rico Ver ssimo, Jules Verne, Monteiro Lobato, Alexandre Dumas, and others when he was 7. At age 12, he discovered his next two passions: playing and creating games (by that time on his first Apple computer), and writing. Many years later he's about forty now these passions still flourish. Now he's a teacher of academic game development courses, has written four books on the topic, and has participated in Brazilian gamse development contests, both as a contestant and as a judge. He has also written short story books, children's books, and young adult books, and in 2008 he released his first romance, The Name of the Eagle, currently available only in Portuguese. And, of course, he still loves to read, some favorite authors being Ken Follett and Paulo Coelho. His ultimate passions starting in 1995 and still burning are his wife, Wal ria, and his kids, Nat lia and Rafael. Alexandre believes that lives needs passion to be lived entirely, and hopes that this book helps light this passion in readers' hearts. You can find his work at AlexandreLobao.com.

Most helpful customer reviews

6 of 6 people found the following review helpful.
Great learning value!
By Amazon Customer
You should understand C# code before diving into this book. I tried online tutorials and nothing comes close to just reading and using this book! Although there were a few places where I had to use an online resource to figure out exactly what the author was talking about, it still supasses any other online XNA intro.

3 of 3 people found the following review helpful.
Best XNA book, code examples contain errors, where is the Quality Control?
By Milford Hughes
I found this book on the web and still decided to buy it. The book is the easiest time I think I have ever had learning XNA, however, like all programming books it seems that only experienced coders who correct errors as they read are the ones in charge of editing and quality control.

For example, on page 46 it tells you to include a line of code that doesn't seem to make sense (private SpriteBatch spriteBatch = null;) in the Game1 code. This of course is redundant and cause the game not to compile. And.... naturally, the downloaded source code runs fine. Why? Because this line of code is not in the project. I imagine the XNA guru they had reviewing this book (how come they don't hand the book to a total newbie and say 'here, follow this book exactly and tell us when the code examples dont work') fixed the errors he seen on the fly without thinking ..oh, a total newbie won't know this is an obvious mistake..

But I can honestly say I have NEVER read a 'teach yourself' programming book with flawless code examples. And of course the downloaded source always works and you just have to compare your file with thier file and see what is different. The only positive note I can say about the poor state of quality control with newbie programming books in general is that in a way it teaches you to troubleshoot code. But, for someone who is completely new and doesn't pick up on these things it is very frustrating. I'm lucky now in that I have learned enough that I can fix these errors, but a few years ago I would have just tossed this book out of frustration when I do exactly as instructed and it still doesnt work.

To the people who write these books I have a suggestion....

If the person in charge of quality control has ever written a single line of code they are not qualified to review a book targeting newbies. Give the book to your spouse, neighbor, 12 year old, etc. who will quickly hand it back to you 5 times every chapter and say 'hey, I did what it said and got a bunch of errors', or 'hey, it assumes here on page whatever I know where to type this'.

Now, all that being said, this is a darn good book. The authors make XNA and XBOX programming about as simple as possible... the examples are explained very well and easy to follow. If you have gone through another C# teach yourself newbie book you should minimal trouble getting a game up and running in just an hour or so!

5 of 6 people found the following review helpful.
Best XNA book on the market
By MD
This is a great book to help you get started with XNA. I like the fact that it's straight and to the point with no fluff. Covers 2D and 3D game programming including skeletal animation. All sample code compiles and runs as advertised and is explained in detail. I had a bad experience with another XNA book so I'm glad I found this one.

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Beginning XNA 2.0 Game Programming: From Novice to Professional, by Alexandre Santos Lobao, Bruno Evangelista, Jose ANTONIO LEAL DEFARIAS PDF
Beginning XNA 2.0 Game Programming: From Novice to Professional, by Alexandre Santos Lobao, Bruno Evangelista, Jose ANTONIO LEAL DEFARIAS PDF

[J210.Ebook] Free PDF Write & Wrong: Writing Within Criminal Justice Student Workbook, by Caroline W. Ferree, Heather Pfeifer

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Write  &  Wrong: Writing Within Criminal Justice Student Workbook, by Caroline W. Ferree, Heather Pfeifer

Written reports and other types of writings by criminal justice and social science professionals can directly affect people's lives. Thus, it is crucial for the writer to effectively convey his or her message in a coherent and organized manner. Write & Wrong: Writing Within Criminal Justice Student Workbook is a comprehensive workbook that guides students through the entire process of writing an academic-style paper, by teaching them how to conduct library research, how to take notes without plagiarizing, how to cite in proper APA style, and how to complete a final draft of a paper. The Student Workbook includes hands-on writing exercises and reference guides to further help improve the students’ writing skills. The Second Edition also helps students prepare for entering the job market, by discussing how to write a professional résumé and cover letter, how to prepare PowerPoint presentations, and how to write a variety of professional reports.

  • Sales Rank: #58952 in Books
  • Published on: 2016-12-26
  • Original language: English
  • Number of items: 1
  • Dimensions: 10.00" h x 9.00" w x 1.00" l, .0 pounds
  • Binding: Paperback
  • 300 pages

Most helpful customer reviews

0 of 0 people found the following review helpful.
GREAT BUY!!!
By Monica Lewis
This book gives students detailed use regarding APA format and priced reasonably.

0 of 0 people found the following review helpful.
Five Stars
By Amazon Customer
Excellent book

0 of 1 people found the following review helpful.
Five Stars
By Amazon Customer
Very good

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Monday 18 August 2014

[Y750.Ebook] Ebook Free A Darker Shade of SwedenFrom Mysterious Press

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A Darker Shade of SwedenFrom Mysterious Press

Ever since Stieg Larsson shone a light on the brilliance of Swedish crime writing with his critically acclaimed and internationally bestselling novel, The Girl with the Dragon Tattoo, readers around the world have devoured fiction by some of the greatest masters of the genre. In this landmark publication, Sweden’s most distinguished crime writers, including Stieg Larsson himself, have contributed stories to an anthology that promises to sate the desire to read about the dark side of Sweden.

With an introduction by Swedish crime authority John-Henri Holmberg that traces the evolution of the genre from the late nineteenth century to the present-day, this volume includes a never-before-translated story from Maj Sj�wall and Per Wahl��, the husband-and-wife team that brought Swedish crime to a worldwide audience for the first time in the 1960s and 70s; a brilliantly orchestrated piece in which Henning Mankell’s Kurt Wallander meets H�kan Nesser’s Van Veeteren; and stories from writers who will define the next wave of Swedish crime fiction.

Containing seventeen stories never before published in English, A Darker Shade of Sweden delves into the deepest shadows of this captivating place and shows why Swedish crime has kept readers enthralled for decades.

  • Sales Rank: #1714835 in Books
  • Published on: 2014-12-16
  • Original language: English
  • Number of items: 1
  • Dimensions: 8.20" h x 1.10" w x 5.40" l, .0 pounds
  • Binding: Paperback
  • 352 pages

Review
"A wonderful collection of beautiful Nordic noir—with Stieg Larsson as the cherry on top."—Camilla Lackberg

“A fine anthology . . . [and] editor Holmberg gives an excellent overview of Swedish crime fiction in his introduction.”—Mystery Scene

“Gripping. . . . These unsettlingly dark tales reaffirm the dominance of Swedish writers with original crime fiction.”—Sun (UK)

“Entertaining.”—Times (UK)

About the Author
John-Henri Holmberg is the Edgar Award-nominated coauthor of the 2011 book The Tattooed Girl, about the Millenium novels and their author, Stieg Larsson, who was a personal friend. He has written books on science fiction, psychological thrillers, adult fantasy fiction, and film, and lectured on popular fiction, particularly crime and science fiction. For more than fifteen years he reviewed crime for Sweden's largest daily newspaper, which gained him the Jan Broberg Excellence in Criticism award, as well as election to the Swedish Crime Fiction Academy. He is now a full-time writer, translator, and editor, living with his family on the southern coast of Sweden.

Most helpful customer reviews

34 of 34 people found the following review helpful.
Excellent
By P. Schumacher
This is a collection of mystery stories by some of the foremost writers in Sweden now.

It's terrific--a great way to sample some authors you may not know about.

It has some well-known ones--Stieg Larsson, Henning Mankell, Hakan Nesser, Sjowall/Wahloo--but also some not-so-well-known outside Sweden.

And in fact, in my view, the best stories are the ones by lesser-known authors.

The range is astounding. Everything from mystery/sci fi (Stieg Larsson) to history (Asa Larsson) to mystery/horror (Tove Alsterdal) to history/diary (Sara Stridsberg).

One problem I have with short stories is that when they are good they're too short, and when they are bad they're too long. That isn't the case here. The best one (and they are all VERY good) may be the shortest: Sara Stridsberg's "Diary Braun." This purports to be the words or thoughts of Eva Braun, Hitler's mistress, on the eve of her destruction. It isn't really a mystery, but it is brilliant and creepy and surprisingly sad.

My favorite, however, is "The Mail Run" by Asa Larsson. The mystery component is not the best part. The best part, as always with Asa Larsson, is the characterization. The relationship between the sheriff and his morose wife is heart-wrenching, touching, stunning.

A really fine collection. Get it and try it out.

15 of 15 people found the following review helpful.
A good collection of Swedish crime stories
By Laura A. Wideburg
If you have not yet started to read Swedish crime novels and would like an overview of what is out there before buying individual authors' books, this is a good place to start. Authors already well-known in the United States as well as authors mostly known in Sweden or Europe are represented. The editor has written an excellent summary of the history of Swedish crime writing during the past 100 years and how the modern authors follow this tradition.

14 of 15 people found the following review helpful.
enjoying Swedish crime fiction
By kmc
Ever since "Girl with the Dragon Tattoo" and "Wallander", readers and viewers have been looking to Sweden for more "new" (to us) voices, new characters, and new settings in this idealized and still foreign land. (I've visited Sweden three times, and sometimes I think I should emigrate.) This place and their culture are at once familiar and strange, like a parallel world. These authors may not have written for their new global audience, but they have reached us. And now we have this sampler, and now we can hope for more.

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Streptomyces in Nature and Medicine: The Antibiotic Makers, by David A. Hopwood

This is an insiders account of 50 years of genetic studies of the soil-inhabiting microbes that produce most of the antibiotics used to treat infections, as well as anti-cancer, anti-parasitic and immunosuppressant drugs. The book begins by describing how these microbes the actinomycetes were discovered in the latter part of the nineteenth century, but remained a Cinderella group until, in the 1940s, they shot to prominence with the discovery of streptomycin, the first effective treatment for tuberculosis and only the second antibiotic, after penicillin, to become a medical marvel. There followed a massive effort over several decades to find further treatments for infectious diseases and cancer, tempered by the rise of antibiotic resistance consequent on antibiotic misuse and over-use. The book goes on to describe the discovery of gene exchange in the actinomycetes in the context of the rise of microbial genetics in the mid-20th century, leading to determination of the complete DNA sequence of a model member of the group at the turn of the millennium. There follow chapters in which the intricate molecular machinery that adapts the organisms metabolism and development to life in the soil, including antibiotic production, is illuminated by the DNA blueprint. Then come an up-to-the minute account of the use of genetic engineering to make novel, hybrid, antibiotics, and a topical description of techniques to learn the roles of the thousands of genes in a genome sequence, throwing a powerful light on the biology of the organisms and their harnessing for increasing antibiotic productivity. In the final chapter we return to the mycobacteria that cause tuberculosis and leprosy, the first actinomycetes to be discovered, and how methodology, in part derived from the study of the streptomycetes, is being applied to understand and control these still deadly pathogens.

  • Sales Rank: #2971257 in Books
  • Published on: 2007-02-03
  • Original language: English
  • Number of items: 1
  • Dimensions: 6.30" h x 1.00" w x 9.20" l, 1.31 pounds
  • Binding: Hardcover
  • 272 pages

Review

"Overall this is an extremely well written book, with a clear and concise narrative that is immensely readable. I would highly recommend it to anyone with an interest in the history of bacteriology, microbial genetics or antibiotics."--Microbiology Today


"The book is excellently written throughout and the attention to detail is phenomenal...I thoroughly recommend this book to those with an interest in the history of microbiology, microbial genetics, and antibiotics...It will not disappoint and should be on the reading list of all new graduate students in steptomyces laboratories the world over."--Microbe


"...an insider's account of the discoveries in Steptomyces genetics over the last half-century, and the applications of genetic technologies to develop novel medicinies...Overall, the language is very accessible to the non-specialist reader. New concepts are fully introduced and explained clearly...I enormously enjoyed reading this book."--Immunology News


About the Author
David Hopwood is a Professor Emeritus of Genetics at the University of East Anglia.

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1 of 1 people found the following review helpful.
A good deep dive on Strep
By Laurence Chalem
If you're looking for in-depth--history, not technical--information on this genera of bacteria, then this book is for you. Recommended... - lc

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Sunday 17 August 2014

[Y348.Ebook] Ebook Free Interview Magazine June/July 2014 Jamie Dornan Fifty Shades of Grey Cover

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  • Sales Rank: #5880416 in Books
  • Published on: 2014
  • Binding: Single Issue Magazine

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Sunday 3 August 2014

[S280.Ebook] Download Sample Size Calculations in Clinical Research, by Shein-Chung Chow, Jun Shao, Hansheng Wang

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Sample Size Calculations in Clinical Research, by Shein-Chung Chow, Jun Shao, Hansheng Wang

Sample size calculation plays an important role in clinical research. It is not uncommon, however, to observe discrepancies among study objectives (or hypotheses), study design, statistical analysis (or test statistic), and sample size calculation. Focusing on sample size calculation for studies conducted during the various phases of clinical research and development, Sample Size Calculation in Clinical Research explores the causes of discrepancies and how to avoid them.

This volume provides formulas and procedures for determination of sample size required not only for testing equality, but also for testing non-inferiority/superiority, and equivalence (similarity) based on both untransformed (raw) data and log-transformed data under a parallel-group design or a crossover design with equal or unequal ratio of treatment allocations. It contains a comprehensive and unified presentation of statistical procedures for sample size calculation that are commonly employed at various phases of clinical development. Each chapter includes, whenever possible, real examples of clinical studies from therapeutic areas such as cardiovascular, central nervous system, anti-infective, oncology, and women's health to demonstrate the clinical and statistical concepts, interpretations, and their relationships and interactions.

The book highlights statistical procedures for sample size calculation and justification that are commonly employed in clinical research and development. It provides clear, illustrated explanations of how the derived formulas and/or statistical procedures can be used.

  • Sales Rank: #4004501 in eBooks
  • Published on: 2003-03-04
  • Released on: 2003-03-04
  • Format: Kindle eBook

Review
This well composed book … contains sample size formulas and examples. … [A] good reference book for researchers in clinical trials.
- Journal of Statistical Computation & Simulation, Vol. 74, No. 5, May 2004

The reference list contains details of an excellent collection of articles. The examples are clearly illustrated. This is a fascinating book, and applied statisticians, health and medical researchers will like it a lot. Statistical consultants will be fond of the book as a reference guide.
-Journal of Statistical Computation and Simulation, Vol. 75, No. 9, Sept 2005

Review
"This well composed book contains sample size formulas and examples. [A] good reference book for researchers in clinical trials." - Journal of Statistical Computation & Simulation, Vol. 74, No. 5, May 2004

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30 of 30 people found the following review helpful.
sample size an important aspect of trial design
By Michael R. Chernick
The authors of this book have a great deal of clinical trial experience in the pharmaceutical industry as well as strong academic backgrounds. For the clinical trial statistician there is now a rich supply of software products to aid in the determination of sample size for a variety of modeling situations. So knowing formulas is no longer important. What is important is to understand the basis for the formulas. This book provides the industrial perspective and the main fixed sample size designs. In this industry trials are constructed to show superiority, noninferiority and equivalence. These three distinct appoaches lead to different results because the null and alternative hypotheses change as you change your goal from superiority to equivalence.

This book makes that important distinction and is very scholarly, providing many of the relevant references. Although most clinical trials are still parallel design randomized controlled trials with fixed sample size, there are more and more trials that allow for sequential decisionmaking and hence the actual total sample size can be subject to randomness. The group sequential trials have been the most successful in this regard. But now there are also more flexible "adaptive designs" that are being used. For group sequential designs see the text by Jennison and Turnbull and for the adaptive designs Chow and Chang and a more recent applied text by Chang are very good sources of information. Software packages that are available to do group sequential and adaptive designs are East by Cytel, Seq+Trials by Insightful Corp., PASS by Number Crunchersand ADDPLAN by a German Company. Also statisticians like Mark Chang and Keaven Anderson have created their own routines for adaptive designs using the R programming language.

29 of 31 people found the following review helpful.
nice coverage of typical sample size problems in clinical trials
By Michael R. Chernick
This is the second edition of a very popular book on sample size estimation that is a valuable reference for any statistician in the industry. we all need to go through such expercises at the beginning of a trial as part of the protocol development.

One disappointment I have with the book is that it does not delineate new topics and other changes/additions from the first edition. Often this is covered by having two Prefaces, the original one from the first edition and a new one from the second edition. The authors unfortunately did not choose to do that. So an owner of the first edition would have to scan through both books to identify the changes.

Another disappointment is the lack of reference to any existing software to do sample size estimation and these days there are a lot of products available. The programs nQuery Advisor and Power and Precision handle equivalence, superiority and noninferiority problems for continuous data. They also provide approximate and exact methods for binomial data. Other packages such as StatXact handle sample size estimation for exact binomial tests as well as for Fisher's Exact test. PASS, S+SeqTrial and East are packages that provide the designs and sample size stopping rules for group sequential procedures and in some cases adaptive designs. Also with the development of version 9 of SAS comes the new procedures power and glmpower that do everything that nQuery can handle.

The value of the book is that it develops the methodology and therefore helps with the understanding of how and when to use the various procedures. Traditional tables that use to be important for sample size calculations are now obsolete given the availability of good software tools. Although the book goes to great lengths to cover almost any application. Most of these applications can be handled these days through the available software packages.

I can definitely recommend this book as a fine reference on sample size estimation for the wide range of trial applications. I would only try to encourage the authors to drop the use of tables and get up to date by recommending the appropriate software for the various applications.

0 of 0 people found the following review helpful.
Four Stars
By June E. Nezamis
Good reference

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